The NFL stage is set for an intriguing face-off as the New England Patriots are scheduled to play against the San Francisco 49ers on September 29, 2024, at Levi’s Stadium in Santa Clara, starting at 4:05 PM.

Currently, the Patriots hold a position of second in their division and sixth in the conference with a record of 1-1-0, reflecting a winning percentage of 0.50. They have gathered a total of 36 points while conceding 33, maintaining a positive net point difference of 3.

The 49ers, on the other hand, rank third in their division and eleventh in their conference, also sporting a 1-1-0 record and a 0.50 win rate. They have scored a robust 49 points and have allowed 42 points, resulting in a net difference of 7.

In their previous outing, the Patriots were narrowly defeated with a scoreline of 20-23 by SEA at Gillette Stadium. They secured 19 first downs, along with 185 rushing yards and 125 passing yards. The 49ers, facing MIN at U.S. Bank Stadium, concluded their game at 17-23, with 24 first downs, 102 rushing yards, and an impressive 294 passing yards.

Jacoby Brissett, the Patriots’ quarterback, completed the last game with 149 passing yards and one touchdown, registering a passer rating of 83.72. The 49ers’ quarterback, Brock Purdy, threw for 319 yards and one touchdown, achieving a passer rating of 101.27.

Betting Overview:
The San Francisco 49ers are favored with a point spread of -12.00, reflecting their home advantage and perhaps a slight edge in recent performances. Conversely, the New England Patriots are positioned with a point spread of +12.00. The total for the game is set at an over/under of 43.50 points, suggesting expectations of a moderately high-scoring game. The moneyline presents the 49ers as strong favorites at -600, while the Patriots stand as underdogs with +430 odds. This scenario provides a compelling prospect for bettors looking for potential upsets or sure wins.